Below is a list of key references in molecular pathological epidemiology (MPE).
Introduction of MPE
Ogino S, et al. Annu Rev Pathol 2019. https://pubmed.ncbi.nlm.nih.gov/30125150/
Ogino S, et al. Epidemiology 2016;27:602-611. https://www.ncbi.nlm.nih.gov/pubmed/?term=26928707
Ogino S, et al. Gut 2011 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040598/ (GWAS-MPE approach)
Integration of microbiology, microbiomics, immunology, and immunomics into MPE
Inamura K, et al. Gut (online).
Ogino S, et al. Gut 2018.
Lifecourse MPE research (for early-onset cancer)
Ugai T, et al. Nat Rev Clin Oncol 2022 (early-onset cancers in many organs)
Akimoto N, et al. Nat Rev Clin Oncol 2021 (early-onset colorectal cancer)
Nishi A, et al. Am J Prev Med 2015.
Epidemiological paradox solving
Nishihara R, VanderWeele TJ, Shibuya K, Mittleman MA, Wang M, Field AE, Giovannucci E, Lochhead P, Ogino S. Eur J Epidemiol 2015. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639412/
The unique disease principle, the fundamental theory behind MPE
Ogino S, et al. Mod Pathol 2013 http://www.nature.com/modpathol/journal/v26/n4/full/modpathol2012214a.html
Ogino S, et al. Expert Rev Mol Diagn 2012 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492839/
The etiologic field effect model
Lochhead P, Chan AT, Nishihara R, Fuchs CS, Beck AH, Giovannucci E, Ogino S. http://www.nature.com/modpathol/journal/v28/n1/full/modpathol201481a.html
Papers (selected) on methods to investigate etiologic heterogeneity
Wang M, Spiegelman D, Kuchiba A, Lochhead P, Kim S, Chan AT, Poole EM, Tamimi R, Tworoger SS, Giovannucci E, Rosner B, Ogino S. Statistical methods for studying disease subtype heterogeneity. Stat Med 2016;35:782-800. https://www.ncbi.nlm.nih.gov/pubmed/26619806
Wang M, Kuchiba A, Ogino S. Am J Epidemiol 2015 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517696/
Meeting and symposium proceedings related to MPE, including the International MPE Meeting Series
Ogino S, Campbell PT, Nishihara R, Phipps AI, Beck AH, Sherman ME, Chan AT, Troester MA, Bass AJ, Fitzgerald KC, Irizarry RA, Kelsey KT, Nan H, Peters U, Poole EM, Qian ZR, Tamimi RM, Tchetgen Tchetgen EJ, Tworoger SS, Zhang X, Giovannucci EL, van den Brandt PA, Rosner BA, Wang M, Chatterjee N, Begg CB. Cancer Causes Cont 2015
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466011/
Campbell PT, Rebbeck TR, Nishihara R, Beck AH, Begg CB, Bogdanov AA, Cao Y, Coleman HG, Freeman GJ, Heng YJ, Huttenhower C, Irizarry RA, Kip NS, Michor F, Nevo D, Peters U, Phipps AI, Poole EM, Qian ZR, Quackenbush J, Robins H, Rogan PK, Slattery ML, Smith-Warner SA, Song M, VanderWeele TJ, Xia D, Zabor EC, Zhang X, Wang M, Ogino S. Proceedings of the Third International Molecular Pathological Epidemiology (MPE) Meeting. Cancer Causes Cont (in press). https://www.ncbi.nlm.nih.gov/pubmed/28097472